首先是项目估值的系统性提升，MNC对中国创新药资产的估值正在明显上涨，即使早期项目也能获得高额首付款。在石药集团与阿斯利康的合作中的12亿美元首付款，仅次于2025年三生制药与辉瑞就PD-1/VEGF双抗达成的12.5亿美元首付款纪录。
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