8Agarose is used in electrophoresis, chromatography, immunodiffusion assays, cell and tissue culturing, and other applications. It is the electrically neutral, non-sulphated, gelling component of agar. While its market is smaller, it is fundamental for specialized biochemical and analytical protocols.
Stream implementations can and do ignore backpressure; and some spec-defined features explicitly break backpressure. tee(), for instance, creates two branches from a single stream. If one branch reads faster than the other, data accumulates in an internal buffer with no limit. A fast consumer can cause unbounded memory growth while the slow consumer catches up — and there's no way to configure this or opt out beyond canceling the slower branch.
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